반응 #7039

반응 방정식

7-azaindole

butyraldehyde

→

1,1-di-(7-azaindol-3-yl)-butane

수율 15.0%

반응 조건

후처리

1. 1
   기타ST 1436 was prepared
2. 2
   기타The reaction
3. 3
   온도however, was heated
4. 4
   온도under reflux for 48 hours
5. 5
   기타The end product was isolated
6. 6
   기타purified chromatographically on a silica column
7. 7
   세척eluting with a CH2Cl2

실험 절차

ST 1436 was prepared as described in example 2/2 from 7-azaindole and butyraldehyde. The reaction, however, was heated under reflux for 48 hours. The end product was isolated and purified chromatographically on a silica column eluting with a CH2Cl2:CH3COCH3 gradient ranging from 9:1 to 4:6. Yield 15%.

출처