반응 #70344

ord-173a0ffe83b349cd963070606fb7fc29

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    기타The solvent was evaporated
  2. 2
    기타the residue was triturated in diethyl ether
  3. 3
    기타The solid formed
  4. 4
    여과was filtered off
  5. 5
    기타to afford

실험 절차

A solution of 5-methyl-2-(6-morpholinopyridin-3-ylamino)benzoate tert-butyl ester in TFA (0.6 ml, 7.58 mmol) was stirred at room temperature for 1 hour. The solvent was evaporated and the residue was triturated in diethyl ether. The solid formed was filtered off to afford 0.047 g (73% of yield) of the expected product.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US08536165B2uspto-grants-2013_09