반응 #70335
ord-809ac7c483c042138138339ab910d6cd
반응 방정식
시약
없음
반응 조건
온도
60°CELSIUS
상세 조건
See reaction.notes.procedure_details.
후처리
- 1기타the solvent was evaporated
- 2기타the solid obtained
- 3추출extracted with CHCl3
- 4기타The crude mixture was purified over a SCX cartridge
실험 절차
The solid residue obtained in step A was dissolved in 2.5 ml of ethanol and 0.180 ml of aqueous solution 2N NaOH were added. The mixture was heated at 60° C. for 2 hours, the solvent was evaporated and the solid obtained was suspended in water. The pH was taken to 6.5 and extracted with CHCl3. The crude mixture was purified over a SCX cartridge eluting with MeOH/NH3 10:1 affording 0.025 g (yield 77%) of the expected product.