반응 #70042

반응 방정식

1-isocyano-2-methylpropan-2-yl methyl carbonate

1H-benzo[d]imidazol-5-amine

4-(4-hydroxypiperidin-1-yl)benzaldehyde

sodium tert.-butoxide

mono-tert-butyl malonate

→

1-(1H-Benzo[d]imidazol-5-yl)-5-(4-(4-hydroxypiperidin-1-yl)phenyl)-pyrrolidine-2,4-dione

반응 조건

후처리

1. 1
   기타The compound was synthesized

실험 절차

The compound was synthesized starting from 1H-benzo[d]imidazol-5-amine (0.970 g, 7.3 mmol), 4-(4-hydroxypiperidin-1-yl)benzaldehyde (1.5 g, 7.3 mmol), mono-tert-butyl malonate (1.17 g, 7.3 mmol), 1-isocyano-2-methylpropan-2-yl methyl carbonate (1.15 g, 7.3 mmol) and sodium tert.-butoxide (1.5 g, 14.6 mmol) according to method 5.

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