반응 #70030

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ethyl 2-[(1H-benzo[d]imidazol-5-yl)({[4-(morpholin-4-yl)phenyl]({2-[(methoxycarbonyl)oxy]-2-ethylpropyl}carbamoyl)methyl})-carbamoyl]acetate

potassium tert.-butoxide

→

Ethyl 1-(1H-benzo[d]imidazol-5-yl)-5-(4-morpholinophenyl)-2,4-dioxopyrrolidine-3-carboxylate

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후처리

1. 1
   기타The compound was synthesized
2. 2
   기타may be prepared in accordance with the procedure

실험 절차

The compound was synthesized starting from ethyl 2-[(1H-benzo[d]imidazol-5-yl)({[4-(morpholin-4-yl)phenyl]({2-[(methoxycarbonyl)oxy]-2-ethylpropyl}carbamoyl)methyl})-carbamoyl]acetate (which may be prepared in accordance with the procedure described for Intermediate 4; 0.38 g, 0.638 mmol) and potassium tert.-butoxide solution (1M, 1.276 ml, 1.276 mmol) according to the method described in Step 2.

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