반응 #70029

반응 방정식

ethyl 2-[(1H-benzo[d]imidazol-5-yl)[2,3,5-trifluorophenyl({2-[(methoxycarbonyl)oxy]-2-methylpropyl}carbamoyl)methyl]-carbamoyl]acetate

potassium tert.-butoxide

→

Ethyl 1-(1H-benzo[d]imidazol-5-yl)-2,4-dioxo-5-(2,3,5-trifluorophenyl)pyrrolidine-3-carboxylate

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후처리

1. 1
   기타The compound was synthesized
2. 2
   기타may be prepared in accordance with the procedure

실험 절차

The compound was synthesized starting from ethyl 2-[(1H-benzo[d]imidazol-5-yl)[2,3,5-trifluorophenyl({2-[(methoxycarbonyl)oxy]-2-methylpropyl}carbamoyl)methyl]-carbamoyl]acetate (which may be prepared in accordance with the procedure described for Intermediate 3; 0.153 g, 0.271 mmol) and potassium tert.-butoxide solution (1M, 0.542 ml, 0.542 mmol) according to the method described in step 2.

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