반응 #70003

반응 방정식

TFA

octadeca-9,12-dienoic acid (E)-3-adamantan-1-yl-4′-(2-tert-butoxycarbonylvinyl)biphenyl-4-yl ester

→

title compound

수율 99.0%

(E)-Octadeca-9,12-dienoic acid 3-adamantan-1-yl-4′-(2-carboxyvinyl)-biphenyl-4-yl ester

수율 99.0%

용매

DCM

반응 조건

후처리

1. 1
   기타The solvent was removed under reduced pressure

실험 절차

TFA (1.6 ml) was dropped into an ice-cooled solution of octadeca-9,12-dienoic acid (E)-3-adamantan-1-yl-4′-(2-tert-butoxycarbonylvinyl)biphenyl-4-yl ester (110 mg, 0.159 mmol) in DCM (1.6 ml) and the resulting solution was stirred for 30 min at 0° C. The solvent was removed under reduced pressure to obtain the title compound as a white solid (100 mg, 99%).

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