반응 #698833

반응 방정식

4-mercapto-2-phenyl-pyrimidine-5-carboxylic acid benzylamide

iodine

→

title compound

수율 87.6%

2-Benzyl-6-phenyl-isothiazolo[5,4-d]pyrimidin-3-one

수율 87.6%

반응 조건

실험 절차

Using the procedure of Example 20, 2.0 g (6.22 mmol) of 4-mercapto-2-phenyl-pyrimidine-5-carboxylic acid benzylamide (from Preparation 42) was reacted with 1.74 g (6.8 mmol) of iodine to give 1.74 g of the title compound after crystallization from isopropanol, mp 166-167° C.

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