반응 #69632
ord-f61fa9f41f904947a2b44754f1fbbe61
반응 방정식
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1추출the solution was extracted three times with EtOAc
- 2건조The combined organic layers were dried (MgSO4)
- 3농축concentrated
실험 절차
To a solution of 2,3-dichloro-6-nitrobenzaldehyde (7.62 g, 34.9 mmol) in tetrahydrofuran (75 mL) was added sodium borohydride (1.31 g, 34.9 mmol) followed by ethanol (1.75 mL), and the mixture was stirred for 1.5 hours. Saturated aqueous ammonium chloride (75 mL) was added, and the solution was extracted three times with EtOAc. The combined organic layers were dried (MgSO4) and then concentrated to give 2,3-dichloro-6-nitrobenzyl alcohol, as an oil which crystallised, 7.62 g (98%).