반응 #690458

반응 방정식

4′,7,8-triacetoxyisoflavone

→

4′,7,8-triacetoxyisoflavan-4-ol

용매

methanol

반응 조건

후처리

1. 1
   기타The catalyst was removed by filtration through Celite
2. 2
   기타the filtrate was evaporated in vacuo

실험 절차

Palladium-on-charcoal (5%, 0.07 g) was added to a suspension of 4′,7,8-triacetoxyisoflavone (0.5 g, 1.3 mmol) in methanol (100 ml) and the mixture was stirred at room temperature under a hydrogen atmosphere for 55 h. The catalyst was removed by filtration through Celite and the filtrate was evaporated in vacuo to yield 4′,7,8-triacetoxyisoflavan-4-ol in quantitative yield. A nuclear magnetic resonance spectrum revealed the product to be a clean 1:1 mixture of cis- and trans-4′,7,8-triacetoxyisoflavan-4-ol. Mass spectrum: m/z 400 (M, 5%); 358 (12); 298 (12); 256 (24); 196 (20); 162 (70); 154 (100); 120 (80).

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