반응 #689385

반응 방정식

N-(piperidin-3-yl)-2-(4-chlorophenyl)-4-methylthiazole-5-carboxamide

3-formyl-4-fluorophenylboric acid

→

desired compound

수율 17.0%

5-[3-[[2-(4-Chlorophenyl)-4-methylthiazol-5-yl]carbonylamino]piperidin-1-yl]-2-fluorobenzaldehyde

수율 17.0%

반응 조건

실험 절차

Using N-(piperidin-3-yl)-2-(4-chlorophenyl)-4-methylthiazole-5-carboxamide (238 mg, 0.709 mmol) and 3-formyl-4-fluorophenylboric acid (238 mg, 1.42 mmol), the same procedure was followed as in Example 2 to give 55.0 mg (17%) of the desired compound as a pale yellow powder.

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