반응 #68838

반응 방정식

4-bromophenol

(chloromethyl)cyclopropane

K2CO3

DMF

→

1-Bromo-4-cyclopropylmethoxybenzene

용매

water

반응 조건

후처리

1. 1
   추출extracted with DCM
2. 2
   건조The organic layer is dried with MgSO4
3. 3
   기타the solvent is removed in vacuo

실험 절차

5.0 g (28.9 mmol) 4-bromophenol, 3.93 g (43.4 mmol) (chloromethyl)cyclopropane and 7.99 g (57.8 mmol) K2CO3 are added to 10 mL DMF and stirred at 80° C. over night. Afterwards the reaction mixture is diluted with water and extracted with DCM. The organic layer is dried with MgSO4 and the solvent is removed in vacuo.

출처