반응 #68770

반응 방정식

8-(4-Methyl-3-nitro-benzoylamino)-naphthalene-1,3,5-trisulfonic acid

→

8-(3-Amino-4-methyl-benzoylamino)-naphthalene-1,3,5-trisulfonic acid

용매

CH3OH

반응 조건

후처리

1. 1
   기타The solution is degassed
2. 2
   기타the disappearance of starting material (12 hrs)
3. 3
   기타The palladium precipitate is removed by filtration through a bed of celite
4. 4
   기타the filtrate is evaporated to dryness

실험 절차

8-(4-Methyl-3-nitro-benzoylamino)-naphthalene-1,3,5-trisulfonic acid (1 eq) and 10% Pd on carbon (10 mol %) are placed in CH3OH. The solution is degassed and an atmosphere of H2 is generated within the reaction vessel. The reaction is allowed to proceed until the uptake of H2 ceases and TLC indicates the disappearance of starting material (12 hrs). The palladium precipitate is removed by filtration through a bed of celite and the filtrate is evaporated to dryness giving the reduced compound 8-(3-Amino-4-methyl-benzoylamino)-naphthalene-1,3,5-trisulfonic acid.

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