반응 #68701
ord-28a9bbf815274b20b6b146529d64edcb
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1기타Under a nitrogen purge
- 2기타for sixteen hours
- 3여과Added chloroform and filtered the reaction mixture through a layer of CELITE
- 4여과filter aid
- 5농축The filtrate was concentrated under reduced pressure to light tan solid
- 6기타The solid was recrystallized from ethanol
실험 절차
Under a nitrogen purge, 10% platinum on carbon (2.0 grams) was added to a mixture of octadecyl 4-nitrobenzoate (23 grams, 55 mmol) and ethyl acetate (230 milliliters) in a Parr vessel. The vessel was placed under hydrogen pressure (49 psi, 3.3×105 Pa) for sixteen hours. Added chloroform and filtered the reaction mixture through a layer of CELITE filter aid. The filtrate was concentrated under reduced pressure to light tan solid. The solid was recrystallized from ethanol to obtain 18 grams of octadecyl 4-aminobenzoate as a white solid.