반응 #686978

반응 방정식

3,4,5-trimethoxyl benzyl bromide

triphenylphosphine

→

3,4,5-trimethoxyl benzyl triphenylphosphine bromide

수율 86.4%

용매

toluene

반응 조건

후처리

1. 1
   workup.DISSOLUTIONdissolving immediately
2. 2
   온도heating
3. 3
   온도to reflux for 1 hour
4. 4
   기타white solid being separated
5. 5
   여과suction filtering
6. 6
   세척washing the filter cake with toluene (30 ml)
7. 7
   기타After vacuum drying

실험 절차

Dissolving 3,4,5-trimethoxyl benzyl bromide (16.05 g, 61.47 mmol) in toluene (150 ml) in a three-necked bottle (250 ml), adding triphenylphosphine (16.12 g, 61.47 mmol) and dissolving immediately, heating to reflux for 1 hour, white solid being separated, cooling to room temperature, suction filtering, and washing the filter cake with toluene (30 ml). After vacuum drying, 3,4,5-trimethoxyl benzyl triphenylphosphine bromide (27.81 g of white powder solid) was isolated, yield: 86.44%.

출처