반응 #684328

반응 방정식

2,2-dibromo-3,3-dimethylbutyric acid

thiocarbohydrazide

methanol

→

4-amino-6-t-butyl-3-mercapto-1,2,4-triazin-5-one

용매

water

반응 조건

후처리

1. 1
   온도to reflux for five hours
2. 2
   기타a solid formed
3. 3
   기타was collected

실험 절차

A mixture of 2,2-dibromo-3,3-dimethylbutyric acid, 55 parts, and thiocarbohydrazide, 22 parts, in 500 parts of (1:1) methanol and water was heated to reflux for five hours. Upon cooling the reaction mixture to 0° C., a solid formed and was collected. The solid, 4-amino-6-t-butyl-3-mercapto-1,2,4-triazin-5-one, was obtained in 78% of theory (29 parts).

출처