반응 #6836

반응 방정식

Acetic acid

3-(2-amino-ethyl)-1H-indol-5-ol hydrochloride

Acetaldehyde

→

2,3,4,9-tetrahydro-1H-β-carbolin-6-ol

용매

methanol

반응 조건

후처리

1. 1
   온도The tube was cooled to rt
2. 2
   기타The solvent was evaporated

실험 절차

Acetic acid was added dropwise to a solution of 3-(2-amino-ethyl)-1H-indol-5-ol hydrochloride (200 mg) in 7 mL of methanol until the pH=4. Acetaldehyde (0.2 mL) was added and the mixture was heated at 75° C. in a sealed tube for 1 h. The tube was cooled to rt and unsealed. The solvent was evaporated yielding 160 mg of 2,3,4,9-tetrahydro-1H-β-carbolin-6-ol.

출처