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9-(trifluoromethyl)-1-(chloromethyl)-6-phenyl-4H-s-triazolo[4,3-a]-[1,4]benzodiazepine

potassium iodide

methylallylamine

→

9-(trifluoromethyl)-1-[(allylmethylamino)methyl]-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine

용매

tetrahydrofuran

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후처리

1. 1
   기타are reacted

실험 절차

In the manner given in Preparation 39, 9-(trifluoromethyl)-1-(chloromethyl)-6-phenyl-4H-s-triazolo[4,3-a]-[1,4]benzodiazepine, potassium iodide and methylallylamine in tetrahydrofuran are reacted to give 9-(trifluoromethyl)-1-[(allylmethylamino)methyl]-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine. Preparation 48 8-Chloro-1-(pyrrolidinomethyl)-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine

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