반응 #6827

반응 방정식

Sodium hydroxide

4-formyl-benzoic acid methyl ester

nitromethane

→

4-(2-nitro-vinyl)-benzoic acid methyl ester

용매

methanol

반응 조건

후처리

1. 1
   기타a precipitate was formed
2. 2
   기타The precipitate was isolated by filtration

실험 절차

Sodium hydroxide (1 N, 2.3 mL) was added dropwise to 4-formyl-benzoic acid methyl ester (0.33 g) and nitromethane (0.11 ml) in 5 mL methanol at 0° C. The solution was acidified after 0.5 h and a precipitate was formed. The precipitate was isolated by filtration to give 228 mg of 4-(2-nitro-vinyl)-benzoic acid methyl ester.

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