반응 #67800

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3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid

intermediate 1

3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid

2-morpholin-4-yl-ethylamine

→

3-(2-Fluoro-4-iodo-phenylamino)-N-(2-morpholin-4-yl-ethyl)-isonicotinamide

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실험 절차

3-(2-Fluoro-4-iodo-phenylamino)-N-(2-morpholin-4-yl-ethyl)-isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.35 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 0.50 mmol of. 2-morpholin-4-yl-ethylamine LC/MS [1.74 min; 471 (M+1)].

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