반응 #67786

ord-eefb4f777a6c4d60abf2477d1e1f9e78

반응 조건

온도
75°CELSIUS
상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    기타The solvent was removed

실험 절차

To a solution of 3-fluoroisonicotinic acid (5.0 g, 35.33 mmol) in acetic acid (25 ml) was added hydrogen peroxide (6 ml). The reaction mixture was stirred at 70-80° C. overnight. The solvent was removed to obtain 5.5 g of 3-fluoroisonicotinic acid 1-oxide in quantitative yield.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US08524911B2uspto-grants-2013_09