반응 #67677

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2-methyl-1-phenylpropan-2-yl 6-bromo-5-hydroxy-3-oxohexanoate

2-methyl-1-phenylpropan-2-yl 6-chloro-5-hydroxy-3-oxohexanoate

→

crude title compound

(3R,5S)-2-methyl-1-phenylpropan-2-yl 6-bromo-3,5-dihydroxy-hexanoate

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후처리

1. 1
   기타prepared in Example 2

실험 절차

The procedure was carried out in the same manner as in Example 3, except that the crude compound (2-methyl-1-phenylpropan-2-yl 6-bromo-5-hydroxy-3-oxohexanoate (7b, 80.0 g) prepared in Example 2 was used in place of (2-methyl-1-phenylpropan-2-yl 6-chloro-5-hydroxy-3-oxohexanoate (7a, 80.0 g). The crude title compound was obtained (12.0 g). A portion of the crude compound was purified by silica gel column (ethyl acetate:n-hexane=3:7(v/v)) to obtain the following NMR data.

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