반응 #676497

ord-0e6b7d98823d4d1ab0247764f0946649

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    온도The mixture is heated
  2. 2
    온도cooled down
  3. 3
    기타Microcapsules are recovered
  4. 4
    세척washed (one or more times)
  5. 5
    여과filtered
  6. 6
    기타dried over night (about 16 h) in a fume hood
  7. 7
    기타at 40° C
  8. 8
    여과The powder is sieved through a 300 μm

실험 절차

Cyclohexane is poured into the microencapsulation reactor. Then, under continuous stirring, fexofenadine HCl, ethylcellulose (EC) and polyethylene are added. The mixture is heated and then cooled down. Microcapsules are recovered, and then washed (one or more times), filtered, and dried over night (about 16 h) in a fume hood or in a hood at 40° C. The powder is sieved through a 300 μm opening sieve.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US09233105B2uspto-grants-2016_01