반응 #674287

ord-9fb1ff1cb2d94f1da5086a474289cc48

반응 방정식

[Ca+2].[Cl-].[Cl-]
calcium chloride
O=P([O-])([O-])O
hydrogen phosphate
[Na+].[OH-]
NaOH
O=P([O-])([O-])[O-].O=P([O-])([O-])[O-].[Ca+2].[Ca+2].[Ca+2]
Calcium Phosphate

용매

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    기타CaP NPs
  2. 2
    기타were obtained by filtration of the suspension through a 0.22 μm
  3. 3
    여과filter
  4. 4
    기타CaP NPs
  5. 5
    기타were stored at 4° C. before use
  6. 6
    기타CaP/ZOL-NPs complexes (CaPZ NPs) were prepared

실험 절차

An aqueous solution of calcium chloride (18 mM) was added, dropwise and under magnetic stirring, to an aqueous solution on dibasic hydrogen phosphate (10.8 mM). The pH of both solutions was adjusted beforehand to 9.5 with NaOH. CaP NPs were obtained by filtration of the suspension through a 0.22 μm filter. CaP NPs were stored at 4° C. before use. CaP/ZOL-NPs complexes (CaPZ NPs) were prepared by mixing a CaP NPs dispersion with an aqueous solution of (50 mg/ml of ZOL in phosphate buffer at pH 9.5), at a volume ratio of 50:1.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US09226897B2uspto-grants-2016_01