반응 #67394

반응 방정식

3,3′,5,5′-tetrakis(dibromoethyl)-1,1′-biadamantane

potassium tert-butoxide

water

→

3,3′,5,5′-tetraethynyl-1,1′-biadamantane

용매

dimethyl sulfoxide

반응 조건

후처리

1. 1
   추출the mixture was extracted 3 times
2. 2
   세척washed with 200 ml of water
3. 3
   건조dried over magnesium sulfate
4. 4
   농축the organic layer was concentrated

실험 절차

The obtained 3,3′,5,5′-tetrakis(dibromoethyl)-1,1′-biadamantane was dissolved in 200 ml of dimethyl sulfoxide, and then 28 g (250 mmol) of potassium tert-butoxide was added at room temperature and the mixture was stirred for 48 hours. The reaction mixture was added to 400 ml of water, the mixture was extracted 3 times using 200 ml of dichloromethane each time and then washed with 200 ml of water and dried over magnesium sulfate, and the organic layer was concentrated to obtain 11.0 g of 3,3′,5,5′-tetraethynyl-1,1′-biadamantane.

출처