반응 #67197

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[7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl 4-methylbenzenesulfonate

2-aminoethanol

→

2-({[7-(METHYLSULFONYL)-2,3-DIHYDRO-1,4-BENZODIOXIN-2-YL]METHYL}AMINO)ETHANOL

용매

ACN

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후처리

1. 1
   기타Preparation

실험 절차

Preparation according to Example 25 using [7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl 4-methylbenzenesulfonate (0.018 g, 0.046 mmol), 2-aminoethanol (0.5 ml), ACN (3 ml). 1H-NMR (400 MHz, CD3OD): δ 7.47 (1H, d, J 2), δ 7.42 (1H, dd, J 8, 2), δ 7.07 (1H, d, J 8.0), δ 4.43 (1H, dd, J 12, 2.4), δ 4.37 (1H, m)), δ 4.09 (1H, dd J 12, 7.2), δ 3.68 (2H, t, J 5.6), δ 3.07 (3H, s), δ 2.94 (2H, m), 2.80 (2H, m) ppm (J-values are in Hz and shifts relative to solvent-peak at 3.31 ppm).

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