반응 #671266

ord-aaf69014045a4df48cfb5c6eab8843aa

반응 방정식

FC(F)(F)c1cc(Br)ccc1Cl
5-bromo-2-chlorobenzotrifluoride
C1CNCCN1
piperazine
FC(F)(F)c1cc(N2CCNCC2)ccc1Cl
title compound
수율 78.2%
FC(F)(F)c1cc(N2CCNCC2)ccc1Cl
1-(4-Chloro-3-trifluoromethyl-phenyl)-piperazine
수율 78.2%

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

Beginning with 5-bromo-2-chlorobenzotrifluoride (602 mg) and piperazine (1 g), 480 mg of the title compound was recovered by the procedure described in Example 1.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US06924374B2uspto-grants-2005_08