반응 #67026

반응 방정식

1-cyclopropyl-4-nitronaphthalene

→

1-amino-4-cyclopropylnaphthalene

수율 73.6%

용매

ethanol

반응 조건

후처리

1. 1
   여과filtered over celite
2. 2
   농축concentrated under reduced pressure
3. 3
   기타The residue was purified by silica gel chromatography

실험 절차

A solution of 1-cyclopropyl-4-nitronaphthalene (5 g, 23 mmol) in ethanol (200 mL) was stirred under hydrogen in the presence of Pd/C (10% net, 1.8 g). The reaction mixture was shaken overnight, filtered over celite, and concentrated under reduced pressure. The residue was purified by silica gel chromatography to yield 1-amino-4-cyclopropylnaphthalene (3.1 g, 73%).

출처