반응 #6701

반응 방정식

4-methoxybenzyl chloride

triphenylphosphine

→

4-methoxybenzyltriphenyl phosphonium chloride

용매

ether

toluene

반응 조건

후처리

1. 1
   온도The resulting solution was refluxed under nitrogen
2. 2
   workup.WAITAfter 8–10 hours
3. 3
   여과The phosphonium salt was collected by filtration

실험 절차

A solution of 4-methoxybenzyl chloride (1.153 g, 0.0074 mol) in anhydrous toluene (10 mL) was treated with triphenylphosphine (1.93 g, 1 equivalent). The resulting solution was refluxed under nitrogen. After 8–10 hours, the reaction was cooled to room temperature and diluted with ether. The phosphonium salt was collected by filtration. Yield=1.5 g (53%); MALDI-TOF MS 383.9 obs. (383.45 calc.).

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