반응 #66947

반응 방정식

4-cyanobenzaldehyde

acetone

NaOH

hydrochloric acid

→

crystals

수율 49.3%

4-(4-Cyanophenyl)-3-buten-2-one

수율 49.3%

용매

water

Water

반응 조건

후처리

1. 1
   기타The precipitated separated solid
2. 2
   여과was collected by filtration
3. 3
   기타dried
4. 4
   기타recrystallized from anhydrous ethanol

실험 절차

Water (150 ml) and 10% NaOH aqueous solution (4.5 ml) were added under vigorous stirring to a solution of 4-cyanobenzaldehyde (7.0 g, 80.6 mmol) in acetone (40 ml) and water(25 ml). The reaction mixture was stirred at 14° C. for 8 hr, after the reaction completed, the reaction mixture was neutralized with 6N hydrochloric acid to adjust pH=7-8.The precipitated separated solid was collected by filtration and dried, then recrystallized from anhydrous ethanol to give 4.8 g of crystals in needles, mp: 102-103° C., yield: 49.25%.

출처