반응 #66814

반응 방정식

ethyl 3-cyano-2-{[(1E)(dimethylamino)methylidene]amino}-4,7-dihydrofuro[2,3-c]pyridine-6(5H)-carboxylate

Ethyl 3-cyano-2-{[(1E)-(dimethylamino)methylidene]amino}-4,7-dihydrofuro[2,3-c]pyridine-6(5H)-carboxylate

3-ethynylaniline

→

title compound

Ethyl 4-[(3-ethynylphenyl)amino]-5,8-dihydropyrido[4′,3′:4,5]furo[2,3-d]pyrimidine-7(6H)-carboxylate

반응 조건

후처리

1. 1
   기타to yield 443 mg (28%)

실험 절차

In analogy to Example 38A, the title compound was prepared from ethyl 3-cyano-2-{[(1E)(dimethylamino)methylidene]amino}-4,7-dihydrofuro[2,3-c]pyridine-6(5H)-carboxylate from Example 37A (1.20 g, 4.14 mmol) and 3-ethynylaniline (968 mg, 8.27 mmol) to yield 443 mg (28%).

출처