반응 #6681

ord-424348839da04f94a84ae091f5ab15fa

용매

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    기타the product was collected by extraction
  2. 2
    세척The organic solution was washed with brine
  3. 3
    건조dried over MgSO4
  4. 4
    기타After evaporation of solvent
  5. 5
    기타pure product was obtained in yield of 100%

실험 절차

35 mmol of benzyl bromide (BzBn, 35 mmol of ethyl 4-hydroxybenzoate (10), 14 g of Cs2CO3 and 40 ml of DMF were combined and stirred at RT ove night. Then the reaction mixture was poured into water and the product was collected by extraction. The organic solution was washed with brine and dried over MgSO4. After evaporation of solvent, pure product was obtained in yield of 100%.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07083832B2uspto-grants-2006_08