반응 #66755

반응 방정식

hydrogen chloride dioxane

tert-butyl 6-(1-methyl-1H-pyrazol-4-yl)-4-oxospiro[chroman-2,4′-piperidine]-1′-carboxylate

→

compound

6-(1-Methyl-1H-pyrazol-4-yl)spiro[chroman-2,4′-piperidin]-4-one hydrochloride

용매

Ether

반응 조건

후처리

1. 1
   여과the resulted precipitate was taken out through filtration
2. 2
   세척washed with ether
3. 3
   기타dried under reduced pressure

실험 절차

4 N hydrogen chloride/dioxane solution was added to tert-butyl 6-(1-methyl-1H-pyrazol-4-yl)-4-oxospiro[chroman-2,4′-piperidine]-1′-carboxylate (1.00 g), and stirred overnight at room temperature. Ether was added to the reaction liquid, the resulted precipitate was taken out through filtration, washed with ether, and dried under reduced pressure to obtain the intended compound as a colorless solid.

출처