반응 #6675

ord-fb80e6a8fc8140659b99210a7b1dab94

반응 방정식

CCN1c2ccccc2Sc2cc(C=O)ccc21
10-Ethylphenothiazine-3-carbaldehyde
NNc1ccccc1
N-phenylhydrazine
CCN1c2ccccc2Sc2cc(C=NNc3ccccc3)ccc21
10-Ethylphenothiazine-3-carbaldehyde-N-phenylhydrazone

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    온도Then, the reaction mixture was refluxed for 0.5 hour
  2. 2
    여과The precipitated product was filtered
  3. 3
    세척washed with a large amount of methanol
  4. 4
    기타dried

실험 절차

10-Ethylphenothiazine-3-carbaldehyde (3 g, 0.012 mol) was dissolved in 30 ml of methanol under mild heating. A solution of 1.9 g (0.018 mol) of N-phenylhydrazine in methanol was added to the cooled reaction mixture. Then, the reaction mixture was refluxed for 0.5 hour. The precipitated product was filtered, washed with a large amount of methanol and then dried. The yield of yellowish crystals of 10-ethylphenothiazine-3-carbaldehyde-N-phenylhydrazone (C21H19N3S, FW=345.00) was 3 g (75%).

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07083884B2uspto-grants-2006_08