반응 #66718
ord-8015c7da29724785a845c1bd61b1ec4b
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1기타formed
- 2여과The reaction mixture was filtered
- 3세척the crystals were washed 1 N HCl
- 4기타dried under vacuum
실험 절차
N-(4-Isopropyl-3-methoxy-phenyl)-acetamide (14.5 g, 69.9 mmol) in 200 ml 6 N HCl was heated to 95° C. for 3.0 hours. The reaction mixture was cooled to room temperature, and allowed to sit for 72 hours at room temperature, during which time crystals formed. The reaction mixture was filtered, and the crystals were washed 1 N HCl and dried under vacuum to give 4-Isopropyl-3-methoxy-phenylamine as an HCl salt (7.6 g, 60%).