반응 #66507

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3-(1-(4-methoxybenzyl)-3-methyl-1H-pyrazol-4-yl)-N-(pyridin-2-yl)-1,2,4-thiadiazol-5-amine

1-(4-methoxybenzyl)-5-methyl-1H-pyrazole-4-carboximidamide

→

3-(3-methyl-1H-pyrazol-4-yl)-N-(pyridin-2-yl)-1,2,4-thiadiazol-5-amine

수율 37.0%

반응 조건

후처리

1. 1
   기타The title compound was prepared

실험 절차

According to Scheme 1 Step 4: The title compound was prepared according to Example 2 Step 4, from a mixture of 3-(1-(4-methoxybenzyl)-3-methyl-1H-pyrazol-4-yl)-N-(pyridin-2-yl)-1,2,4-thiadiazol-5-amine and of 1-(4-methoxybenzyl)-5-methyl-1H-pyrazole-4-carboximidamide (0.11 mmol, 43 mg). 11 mg (43 μmol, 37%) of 3-(3-methyl-1H-pyrazol-4-yl)-N-(pyridin-2-yl)-1,2,4-thiadiazol-5-amine were obtained as a white solid.

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