반응 #66448

반응 방정식

2,4-dichloro-quinazoline

5-methyl-1H-pyrazol-3-yl amine

→

(2-chloro-quinazolin-4-yl)-(5-methyl-1H-pyrazol-3-yl)-amine

용매

ethanol

반응 조건

후처리

1. 1
   여과the resulting precipitate is collected by filtration
2. 2
   세척washed with ethanol
3. 3
   기타dried under vacuum

실험 절차

To a solution of 2,4-dichloro-quinazoline (3.3 g, 16.6 mmol) in anhydrous ethanol (150 mL) is added 5-methyl-1H-pyrazol-3-yl amine (3.2 g, 32.9 mmol). The mixture is stirred at room temperature for 4 h, and the resulting precipitate is collected by filtration, washed with ethanol, and dried under vacuum to afford (2-chloro-quinazolin-4-yl)-(5-methyl-1H-pyrazol-3-yl)-amine.

출처