반응 #66174

반응 방정식

2-chloroquinoline

hydrazine hydrate

→

2-Hydrazinoquinoline

용매

ethanol

반응 조건

후처리

1. 1
   온도under reflux for 16 h
2. 2
   기타the solid formed
3. 3
   여과is filtered off
4. 4
   세척washed with a little ethanol
5. 5
   기타The product is initially air-dried
6. 6
   기타dried under high vacuum

실험 절차

21.0 g (128.4 mmol) of 2-chloroquinoline are initially charged in 210 ml of ethanol. 64.3 g (1.3 mol) of hydrazine hydrate are added, and the mixture is stirred under reflux for 16 h. The mixture is then cooled to 0° C., and the solid formed is filtered off and washed with a little ethanol. The product is initially air-dried and then dried under high vacuum.

출처