반응 #661287

반응 방정식

1b

3-[(3-Amino-4-methylamino-benzoyl)-phenyl-amino]-propionic acid methyl ester

N-(4-cyano-phenyl)-glycine

CDI

→

3-({3-[2-(4-Cyano-phenylamino)-acetylamino]-4-methylamino-benzoyl}-phenyl-amino)-propionic acid methyl ester

용매

THF

반응 조건

후처리

1. 1
   기타After completion of the reaction the mixture
2. 2
   기타was evaporated to dryness
3. 3
   기타the crude product was used without further purification

실험 절차

The product of 1b (23.2 mmol) and N-(4-cyano-phenyl)-glycine (23.2 mmol) were coupled with CDI (23.2 mmol) in dry THF at room temperature. After completion of the reaction the mixture was evaporated to dryness and the crude product was used without further purification.

출처