반응 #66018

반응 방정식

4-fluorodiphenyl ether

chlorosulphonic acid

→

4-(4-fluorophenoxy)benzenesulphonic acid

용매

CH2Cl2

반응 조건

후처리

1. 1
   기타The solvent was evaporated at room temperature
2. 2
   기타the residue dried overnight under vacuum

실험 절차

To a solution of 4-fluorodiphenyl ether 1b (1.00 g, 5.31 mmol) in dry CH2Cl2 (30 mL) under an argon atmosphere at 0° C., was added chlorosulphonic acid (0.35 mL, 5.31 mmol). The reaction mixture was stirred for 2 h at 0° C. The solvent was evaporated at room temperature and the residue dried overnight under vacuum to give the corresponding 4-(4-fluorophenoxy)benzenesulphonic acid (2b) as a pale-pink hygroscopic solid.

출처