반응 #65986

반응 방정식

SnCl2

sodium nitrite

4-benzyloxyaniline

→

product

수율 95.0%

4-Benzyloxyphenylhydrazine hydrochloride

수율 95.0%

용매

HCl

반응 조건

후처리

1. 1
   workup.STIRRINGThe reaction mixture is stirred for 90 minutes at -8° to 10° C
2. 2
   workup.STIRRINGstirred for i hour at 0° C
3. 3
   기타The reaction mixture is removed from the ice bath
4. 4
   workup.STIRRINGis stirred at room temperature for 20 hours
5. 5
   여과The mixture is then filtered
6. 6
   세척washed with water

실험 절차

A solution of sodium nitrite (3.8 g, 0.055 mol in 20 mL of H2O), is added dropwise to an ice cold stirring suspension of 4-benzyloxyaniline (13.0 g, 0.055 mol in 150 mL of concentrated HCl). The reaction mixture is stirred for 90 minutes at -8° to 10° C. A solution of SnCl2 ·2H2O (32.0 g, 0142 mol in 50 mL concentrated HCl) is added and stirred for i hour at 0° C. The reaction mixture is removed from the ice bath and is stirred at room temperature for 20 hours. The mixture is then filtered and washed with water to give 13.0 g (95% yield) of product, m.p. 182°-185° C.

출처