반응 #658768

ord-67ff0ccdf2d04779ba9e16d21b7f7d1e

반응 방정식

O=C1C(=O)c2cccc3cccc1c23
acenaphthenequinone
O=C(Cc1ccccc1)Cc1ccccc1
1,3-diphenyl-2-propanone
[K+].[OH-]
potassium hydroxide
[K+].[OH-]
potassium hydroxide
O=C1C(c2ccccc2)=C2C(=C1c1ccccc1)c1cccc3cccc2c13
7,9-diphenylcyclopenta[a]acenaphthylene-8-one
수율 71.3%

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    온도After the mixture was heated to the reflux temperature
  2. 2
    기타to react for five minutes
  3. 3
    온도The solid substance deposited after cooled on ice
  4. 4
    여과was filtered
  5. 5
    세척washed with ethanol

실험 절차

An amount of 5.9 g (32.4 mmol) of acenaphthenequinone and 7.5 g (35.7 mmol) of 1,3-diphenyl-2-propanone were suspended in 150 ml of ethanol and a solution of 2 g of potassium hydroxide in ethanol was added. After the mixture was heated to the reflux temperature, the same amount of the solution of potassium hydroxide in ethanol was further added and allowed to react for five minutes. The solid substance deposited after cooled on ice was filtered and washed with ethanol to obtain 8.24 g (23.1 mmol) of 7,9-diphenylcyclopenta[a]acenaphthylene-8-one. The yield was 71.3%.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US09028976B2uspto-grants-2015_05