반응 #65804

반응 방정식

1,2-dibromocyclopentene

phenylboronic acid

→

1-bromo-2-phenylcyclopentene

수율 42.0%

반응 조건

후처리

1. 1
   기타Purification by silica gel chromatography (Waters Prep-500) with hexane

실험 절차

Following a synthetic procedure which was similar to the one outlined in Step 2 of Example 1, 4.40 g (19.4 mmol) of 1,2-dibromocyclopentene was reacted with 2.0 g (17.7 mmol) of phenylboronic acid (Aldrich). Purification by silica gel chromatography (Waters Prep-500) with hexane gave 1.61 g (42%) of 1-bromo-2-phenylcyclopentene as an oil: NMR (CDCl3) d 2.01-2.10 (m, 2H), 2.74-2.82 (m, 2H), 2.82-2.90 (m, 2H), 7.27-7.33 (m, 1H), 7.33-7.41 (m, 2H), 7.57-7.63 (m, 2H).

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