반응 #65742

반응 방정식

3-amino-6-chloro-4,5-diethoxycarbonyl-2-phenylpyridine

triethylamine

→

3-Amino-4,5-diethoxycarbonyl-2-phenylpyridine

용매

ethyl acetate

반응 조건

후처리

1. 1
   기타The catalyst was removed by filtration
2. 2
   workup.DISTILLATIONthe solvent was distilled off

실험 절차

A mixture of 100 mg of 3-amino-6-chloro-4,5-diethoxycarbonyl-2-phenylpyridine, 0.08 ml (2.0 eq.) of triethylamine amd 8 ml of ethyl acetate was subjected to catalytic reduction for 7 hours with 100 mg of 10% Pd-C (50% wet). The catalyst was removed by filtration, and the solvent was distilled off. Yield: 86 mg(95.4%).

출처