반응 #657298

반응 방정식

Potassium carbonate

Monochloroacetic acid

potassium carbonate

CO2

hydrazine hydrate

→

2,2′-(hydrazine-1,1-diyl)diacetic acid

용매

water

반응 조건

후처리

1. 1
   기타rose to 70° C
2. 2
   온도The solution was then heated until the gas evolution
3. 3
   기타At the end of the reaction
4. 4
   기타the 2,2′-(hydrazine-1,1-diyl)diacetic acid was precipitated
5. 5
   기타The product (mp 171° C.) was crystallized from water

실험 절차

Monochloroacetic acid (2 eq.) in water was neutralized with potassium carbonate (1 eq.) followed by the addition of hydrazine hydrate (1 eq.). Potassium carbonate (1 eq.) was added to the solution gradually, whereupon, with a steady evolution of CO2, the temperature rose to 70° C. The solution was then heated until the gas evolution stopped. At the end of the reaction, the 2,2′-(hydrazine-1,1-diyl)diacetic acid was precipitated by making the solution acidic with concentrated HCl. The product (mp 171° C.) was crystallized from water, and was confirmed by NMR spectroscopy and elemental analysis.

출처