반응 #657263

반응 방정식

methylphenidate HCl

→

Methylphenidate

용매

water

반응 조건

후처리

1. 1
   기타The wet pellets are dried (Fluid Air Model#0050)
2. 2
   여과sieved (30 mesh<Acceptable<20 mesh)

실험 절차

In a preferred manufacturing process, methylphenidate HCl and microcrystalline cellulose (Avicel PH-101) are blended in a Hobart Mixer. Purified water is added to the dry mixture and the wet granulation is extruded (MG-55 Multi granulator). The extrudate is then spheronized into pellets (Caleva Model# SPH250). The wet pellets are dried (Fluid Air Model#0050) and sieved (30 mesh<Acceptable<20 mesh).

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