반응 #657254

반응 방정식

Ethyl pyrazole-4-carboxylate

NaH

trityl chloride

→

Ethyl 1-tritylpyrazole-4-carboxylate

수율 82.0%

용매

DMF

반응 조건

후처리

1. 1
   기타The title compound was recovered

실험 절차

Ethyl pyrazole-4-carboxylate (W. Holtzer, G. Seiringer, J. Heterocyclic Chem., 1993, 30, 865) (1.7 g, 12.1 mmol) and NaH (680 mg, 60% in mineral oil, 16.94 mmol) reacted in dry DMF for 1 h. Then, trityl chloride (3.373 g, 12.1 mmol) was added, and the reaction mixture stirred for 3 days at room temperature. The title compound was recovered as described in example 2a for 3,5-dimethyl-4-ethylacetate-1-tritylpyrazole. Yield: 82% (3.79 g, 4 mmol).

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