반응 #6566
ord-10fea42bec564443a9bc5ae1ea51daad
반응 방정식
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1온도After heating
- 2온도under reflux for 4 hours
- 3세척washed with ether
- 4추출extracted 4 times with ether
- 5건조The organic phase was dried over sodium sulphate
- 6여과filtered
- 7농축concentrated in a rotary evaporator
실험 절차
5.56 g (99 mmol) KOH flakes were dissolved in 6.82 ml water and 13.65 ml ethanol and then treated with 11.12 g (28.34 mmol) of dibenzyl 2-(3,4,4-trifluoro-3-butenyl)-malonate. After heating under reflux for 4 hours, the reaction mixture was poured into 30 ml water and washed with ether. The aqueous phase was acidified with dilute hydrochloric acid and extracted 4 times with ether. The organic phase was dried over sodium sulphate, filtered and then concentrated in a rotary evaporator.