반응 #65645

반응 방정식

cyclohexylamine

atropic acid

N-methylmorpholine

iso-butyl chloroformate

→

product

수율 28.9%

N-Cyclohexyl-2-phenylpropenamide

수율 28.9%

반응 조건

후처리

1. 1
   기타The crude product was purified by recrystallisation from cyclohexane

실험 절차

This compound was made from atropic acid (10.48 g, 70.8 mmol), N-methylmorpholine (7.8 ml, 70.9 mmol), iso-butyl chloroformate (9.2 ml, 70.9 mmol), and cyclohexylamine (8.1 ml, 70.7 mmol) using the procedure described in Example 3. The crude product was purified by recrystallisation from cyclohexane to give the product (4.69 g), as white crystals, m.p. 131°-133°. (Found: C, 78.7; H, 8.8; N, 5.95. C15H19NO requires C, 78.6; H, 8.35; N, 6.1%.)

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