반응 #65632

반응 방정식

8-chloro-dibenz[b,f]-[1,4]oxazepine

phthalic anhydride

→

title compound

수율 70.3%

2-[(8-chlorodibenz[b,f][1,4]oxazepin-10(11H)-yl)carbonyl]benzoic acid

수율 70.3%

용매

THF

반응 조건

후처리

1. 1
   온도was heated
2. 2
   온도to reflux for 4 days
3. 3
   농축The mixture was concentrated
4. 4
   기타the residue was triturated with ether
5. 5
   여과The precipitated solid was filtered

실험 절차

A stirred mixture of 8-chloro-dibenz[b,f]-[1,4]oxazepine (3.35 g) and phthalic anhydride (2.13 g) in THF (40 mL) was heated to reflux for 4 days. The mixture was concentrated and the residue was triturated with ether. The precipitated solid was filtered to give the title compound as a white solid (3.84 g).

출처